Hypokalaemia and hyperkalaemia

Hypokalaemia and hyperkalaemia.

Disturbances in potassium homoeostasis presenting as low or high serum potassium are common, especially among hospitalised patients. Given the fact that untreated hypokalaemia or hyperkalaemia is associated with high morbidity and mortality, it is critical to recognise and treat these disorders promptly. In this article, normal potassium homoeostasis is reviewed initially and then a pathophysio...

Hyperkalaemia.

Hyperkalaemia is defined as serum potassium concentration greater than 5.5 mmol/l. Its prevalence in the general population is unknown, but it is thought to occur in 1-10% of patients admitted to hospital.1 The rate of morbidity and mortality associated with hyperkalaemia has risen greatly with the use of drugs that target the renin-angiotensin system, and since publication 10 years ago of a ra...

Hypokalaemia.

OBJECTIVE To review the metabolism and function of potassium and causes and management of hypokalaemia. DATA SOURCES A review of studies reported from 1966 to 1998 and identified through a MEDLINE search of the English-language literature of hypokalaemia. SUMMARY OF REVIEW Potassium is predominantly an intracellular ion that contributes to approximately 50% of the intracellular fluid osmola...

Psychogenic vomiting and hypokalaemia.

Chronic hypokalaemia and nephrocalcinosis

Unravelling chronic hypokalaemia can be a clinical challenge in some patients. History and physical examination can be misleading or inaccurate. Diagnostic steps usually involve assessing urinary potassium excretion, transtubular potassium gradient (TTKG) and concomitant acid–base disturbances. In those patients with low urinary potassium excretion, a gastrointestinal cause for the hypokalaemia...